squirmish
unquiet
uneasiness
inquietude
akathisia
unrest
despondency
saddening
blues
sinking feeling
besiege
uneasy
twitchiness
fidgety
ruffle someone's feathers
seizure
sink
cockwaffle
goosebumpy
soreness
agitated depression
qualm
discomfort
irritation
cabin fever
algesthesis
trepidation
agonied
discombobulation
malaise
floating feeling
hypnalgia
irritating
anguishing
funny
heebie-jeebies
painful
anguished
moroseness
sullenness
confusion
anxiety
glumness
asleep
dread fascination
twitter
excruciating
ill-ease
blazes
doddery
disconcerting
sinking
haunt
hyperactivity
wiggles
tense
strain
sombersome
horrify
despairing
discontent
tense up
discontented
thrill
abash
throb
upset
worry
shiver
fretful
yeow
shudder
embarrass
sundowner
tiredsome
quake
nagging
fit
owly
willies
grue
nervousness
uncanny
long face
disturbing
dysphoria
restiveness
upheaval
uncomfortableness
jumpiness
Holy Mother of God
jitteriness

English words for 'showing signs of restlessness resulting from feelings of discomfort or distress.'

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