restless
uneasy
relaxing
restful
reposeful
overrested
sedentary
rest up
rest-cure
camp
haggard
leisured
recharge one's batteries
washed out
out of gas
respite
restlessness
relaxedness
tiresome
have a break
relaxability
queasiness
uneasiness
underexercised
defatigation
spell
laid-back
relaxative
take a break
tired
lay back
unsoundness
holiday
vacation
restfulness
relaxant
aweary
lassitude
weary
comfort zone
cunted
underexercise
pause
veg out
frazzled
lull
ultrarelaxing
unleisuredness
afflicted
impaired
comfort
leisurelessness
underwrapped
comfortableness
catch one's breath
stressless
wan
languid
take a breather
breather
fidgety
naplessness
lie on the oars
rest
relax
ragged
antsy
itchy
unlax
microvacation
unwind
breathe
unstrain
loosen up
make relaxed
nanobreak
fretful
comforting
impecunious
unclench
hard up
live to tell the tale
take it easy
downtime
sleepcation
pinched
hebetude
sedentarily
in straitened circumstances
consolatory
consoling
penniless
penurious
soothing
restless
uneasy
relaxing
restful
reposeful
overrested
sedentary
haggard
leisured
washed out
tiresome
underexercised
laid-back
relaxative
tired
relaxant
aweary
weary
cunted
frazzled
ultrarelaxing
afflicted
impaired
underwrapped
stressless
wan
languid
fidgety
ragged
antsy
itchy
fretful
comforting
impecunious
hard up
pinched
in straitened circumstances
consolatory
consoling
penniless
penurious
soothing
sedentarily
rest-cure
respite
restlessness
relaxedness
relaxability
queasiness
uneasiness
defatigation
spell
unsoundness
holiday
vacation
restfulness
lassitude
comfort zone
underexercise
pause
lull
unleisuredness
comfort
leisurelessness
comfortableness
breather
naplessness
microvacation
nanobreak
downtime
sleepcation
hebetude
rest up
camp
recharge one's batteries
have a break
take a break
lay back
veg out
catch one's breath
take a breather
lie on the oars
rest
relax
unlax
unwind
breathe
unstrain
loosen up
make relaxed
pause
unclench
live to tell the tale
take it easy
English words for 'lacking or not affording physical or mental rest'
As you may have noticed, above you will find words for "lacking or not affording physical or mental rest". Hover the mouse over the word you'd like to know more about to view its definition. Click 
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languid
casual