supermania
nuts
nutballs
off one's dot
distraught
bats
hysterization
cuckoo for Cocoa Puffs
demented
Ophelian
nutcase
reality challenged
maniacal
cracked as an egg
touched
fey
hystericalness
unglued
insanitarily
spaz
hystericize
dad burn
doolally
maddening
certify
drive someone crazy
precious
funny in the head
crazy as a bedbug
phantasmalian
maniacally
phantasmatical
jimjam
one brick short of a full load
lose one's mind
becrazed
insane
loopy
lunatically
ogglesome
dash
daft
mad as a box of frogs
madchild
nucking futs
balmily