cripple
stultify
impotency
powerlessness
impotence
futility
inefficiency
hamstring
shoddiness
flimsiness
nonefficiency
undurability
impoverish
castrate
emasculate
uselessness
helpless
incapacitated
inconstructibility
fragility
insufficient
exhausted
spent
wankle
paltriness
geld
sorriness
unadaptableness
disutility
worst
break down
impuissant
emptiness
undependableness
wash out
no good
unforgivingness
vanity
nonweakness
effectlessness
muscleless
ineffectivity
bypassability
discapacitate
pall
effete
unskillfulness
mug's game
flexibility
incapacity
stulted
fecklessness
uneffective
functionlessness
unworkability
failable
fruitless
toothlessness
unproductivity
stultification
deadening
constipation
underproductivity
boondoggle
good for nothing
tired
impairment
undependability
unreliability
debuggability
imperviability
tireless
impaired
hardworking
industrious
insurmountableness
tenuousness
disutilize
inexertion
unreliableness
noninvincibility
imperviableness
untiring
disaffiliative
non-redundancy
ineffectiveness
infeasibility
inefficacy
unusability
flag
demerit
feckless
unfeasibility
nonunivocity
surmountableness
unimplementability

English words for 'deprive of strength or efficiency; make useless or worthless'

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