bone-chilling
shock to the system
exhausting
draining
unpleasantness
haunting
maleffect
decatenate
hot
afflictively
vile
discomfort
ill effect
ick
negatively
terribleness
cunt
awfulness
dreadfulness
horridness
noxious
drastic
supervirulent
sting
nocent
stick in someone's craw
putrefy
harmfully
baneful
bitch
get to
trouble
pill
in the barrel
subject
attitude
blaring
adversative
blasting
disagreeable
scathand
self-induced
ugliness
unpleasantly
screed
shock
poison
evil day
headache
liable
frustrate
irritably
abradant
apt
upend
set someone's teeth on edge
bearable
supportable
sufferable
degrading
go it blind
miffily
antitherapeutic
asperity
scar
inimical
endurable
injury
poisoned
psychoeffect
afflictingly
agitant
racking
wrenching
trample
pain
with
deleterious
ail
bitter pill to swallow
growlf
sociopetally
overproneness
glancing
overset
offensive
abusive
kerfuffle
beast
by-product
blow
unpleasingness
squick
mood disorder
jar
raise hob

English words for 'With a strong physical or psychological unpleasant effect.'

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