Ernie and Bert
odd couple
mutual friend
pair
mutual friends
Tweedledee and Tweedledum
Tweedledum and Tweedledee
cuddle buddy
friendship
befriending
mate
friendgirl
buddyroo
dotard
twosome
palship
duet
duo
interassociated
philia
couple
galpal
sugar and spice
friendshiplike
personality clash
friend of a friend
co-vilification
friendlihood
romantic friendship
cove
one-to-one
chumship
girlfriend
bodkinwise
cuzzy
battle of the sexes
acegirl
item
bodkin
frenemy
sister from another mister
shag
girl friend
more than friends
chemistry
cognation
acquaintanceship
joined at the hip
opposites attract
daisy chain
alter ego
friendsies
intimacy
buddyhood
love affair
familiarity
closeness
romance
two of a kind
amity
alchemy
interpersonal chemistry
dioecious
kith
correlate
dyad
buddo
friendboy
butterfly
cocker
double
inter-
correlated
correlative
bud
fettler
cut buddy
camaraderie
genderflux
similitude
mutual
frenemyship
bosom
alienating
wifie
pal up
friendshippy
friendshipless
interpersonal
divide
main man
shadow
coalternate
lesbro
multirelational
charva

English words for 'Two inseparable friends whose personalities are vastly different.'

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