disconcert
forset
shit-stir
do one's block
make waves
rile
steam
madden
repulse
lose one's mind
rear
anger
cut up rough
cut up nasty
test someone's patience
drive someone up the wall
consternate
discomfort
overprovoke
rail
get under someone's skin
set up someone's birse
arc up
shake up
spit tacks
have a fit
spit chips
hulk out
importune
mad
lose one's temper
jump salty
storm in
lose one's rag
get one's bowels in an uproar
go ape
upend
poop on
irritate
set someone's teeth on edge
provocate
see red
provoke
outrage
incense
rustle someone's jimmies
brawl
embitter
drive someone crazy
clog
ire
nark
take umbrage
antagonize
antagonise
caseharden
get on someone's tits
spleen
tick off
comb someone's hair the wrong way
rant
draw fire
tickle the dragon's tail
roil