break up
upend
wind up
grieve
go to pieces
confronting
unseat
pain
disturb
anguish
hurt
shake
upsetment
get to
trip
discomfort
distressingly
trying
rock
fuckness
shake up
upsetting
jolt
shock
get one's bowels in an uproar
woeful
lacerate
blow a gasket
stick in someone's craw
flip out
ruffle some feathers
nightmare
ill
devastate
explode
tragic
neuralgia
umbrageous
cut up
sore
play the devil with
too close for comfort
disturbing
lose it
consternate
have kittens
offend
upsettedness
mad
bastard
dere
woe
appalling
eat away at
dismaying
distressing
afflict
distraughtness
heartwrenching
wake up on the wrong side of bed
heartrending
argh
deranged
upsettable
hot-button issue
touch
heartbreaking
gut issue
arc up
disquieting
grizzly
importune
make the feathers fly
trauma
rustle someone's jimmies
to-do
kerfuffle
overemotionalize
flutter
disconcerting
hoo-ha
disruption
torque off
upsettingness
hoo-hah
upsetness
boil someone's piss
butthurt
disturbance
horrify
overset
drive someone up the wall
hurly burly
commotion
high-pressure
grouchy
freak
misery
wig out

English words for 'To upset greatly; to cause great emotional disturbance or unhappiness.'

As you may have noticed, above you will find words for "To upset greatly; to cause great emotional disturbance or unhappiness.". Hover the mouse over the word you'd like to know more about to view its definition. Click search related words by phrase or description. to find a better fitting word. Finally, thanks to ChatGPT, the overall results have been greatly improved.

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