overset
revolt
get to
bother
shake
cut up
discomfort
give someone ass cancer
shake up
enturbulate
get under one's goat
upend
kreistle
get up someone's ass
consternate
rub someone the wrong way
comb someone's hair the wrong way
break up
pain in the ass
trouble
topsy-turvy
overagitate
rustle someone's jimmies
perturb
boil someone's piss
worry
harrow
do someone's head in
pill
mistemper
skeeve
importune
bothering
raise hob
disturbance
regrate
decatenate
ad nauseam
grieve
get on someone's nerves
bitchy-pants
make waves
clog
bust someone's balls
unsoothe
nauseate
naggy
gross out
shudder
convulsive
mither
disconcert
break someone's balls
ruffle some feathers
distress
seethe
set someone's teeth on edge
offend
kerfuffle
nauseating
irk
disrelish
get under someone's skin
worrit
agitate
annoy
tease
derange
eat away at
put the wind up
tarnation
nocent
shuddersome
forget to take one's medication this morning
settle
ail
aggro
pain
conturb
get at
bite the big one
naggle
shock
fret
dismay
squeamish
wind up
irritate
set off
tickle the dragon's tail
make someone's teeth itch
sneed
discommode
subject
bearbait
wig out
distressingly
afflict