get a rise out of
get up someone's nose
chap someone's hide
test someone's patience
provoke
tickle the dragon's tail
make someone's jaw drop
twist someone's balls
discomfort
get in someone's hair
give someone ass cancer
wag a finger
give someone the shits
draw fire
rub up the wrong way
make someone's flesh creep
get someone's back up
raise someone's hackles
break someone's balls
get under someone's skin
curl someone's hair
bust someone's balls
offend
get someone's goat
headdesk
irritate
get on someone's wick
misreact
get under one's goat
tread on someone's toes
mither
bug
gibbet
hit out
comb someone's hair the wrong way
kreistle
neg
turn off
repel
fray
fulminate
get someone's dander up
get someone's Irish up
displease