lose it
lose one's marbles
go potty
craze
madden
over the river and through the woods
get one's freak on
lose one's mind
dumb out
go ham
take leave of one's senses
lunatize
go bonkers
distract
crack up
go mad
stark staring mad
drive someone crazy
obsessively
pop one's cork
not have both oars in the water
go bitchcakes
mad
lima bean
jimjam
come unhinged
reality challenged
mooner
fruitloop
gelt
up the pole
nutballs
tonto
5150
go bananas
wig out
meshuggener
non compos mentis
nut out
unbalance
derange
becraze
maniacal
disorientation
lunatically
nut job
lunatical
half-cracked
craziness
cuckoo for Cocoa Puffs
cooked
obsess
maniac
insaniac
bananas
psycho
nutcase
go moggy
insanity
out of one's box
out of one's tree
off one's box
like nobody's business
one's elevator doesn't go all the way to the top
tripping
mad person
out of one's gourd
mindblow
off one's tree
becrazed
maddening
swivel-eyed
maniacally
loco
insane in the membrane
psychotically
not right in the head
bug out
cuckoo
loony tunes
gobsmacking
hystericize
insanitarily
eleutheromaniac
bonkersdom
moonbatty
gone fishing
off one's chump
hatstand
loon
crackers
nutzoid
nutso
obsessionally
bughouse