lose it
lose one's marbles
go potty
madden
craze
over the river and through the woods
get one's freak on
lose one's mind
dumb out
go ham
take leave of one's senses
lunatize
go bonkers
distract
crack up
go mad
drive someone crazy
pop one's cork
obsessively
stark staring mad
not have both oars in the water
mad
reality challenged
go bitchcakes
lima bean
come unhinged
jimjam
gelt
mooner
fruitloop
nutballs
tonto
up the pole
5150
nut out
go bananas
non compos mentis
unbalance
derange
wig out
meshuggener
becraze
disorientation
maniacal
lunatically
nut job
obsess
craziness
cuckoo for Cocoa Puffs
half-cracked
lunatical
cooked
maniac
nutcase
psycho
bananas
insaniac
go moggy
insanity
becrazed
out of one's tree
off one's tree
off one's box
out of one's box
tripping
out of one's gourd
mad person
like nobody's business
one's elevator doesn't go all the way to the top
mindblow
not right in the head
loony tunes
insane in the membrane
swivel-eyed
bug out
maddening
maniacally
psychotically
loco
cuckoo
gobsmacking
insanitarily
bonkersdom
eleutheromaniac
moonbatty
hystericize
nutso
nutzoid
obsessionally
off one's chump
crackers
gone fishing
loon
hatstand
bughouse