boil someone's piss
give someone ass cancer
get under someone's skin
comb someone's hair the wrong way
neg
provoke
tickle the dragon's tail
get under one's goat
set someone's teeth on edge
raise someone's hackles
drive someone up the wall
get someone's back up
rub up the wrong way
get up someone's ass
importune
get someone's goat
get someone's dander up
give someone the shits
mither
get someone's Irish up
rustle someone's jimmies
shit-stir
grig
do someone's head in
break someone's balls
get on someone's nerves
bust someone's balls
roil
steam
ire
grind one's gears
heated
hock
soreheaded
test someone's patience
inflammatory
spit nails
harass
spit feathers
set up someone's birse
irk
bother
get on someone's tits
irritatingly
nark
drive someone crazy
light the touch-paper
see red
spleen
yechy
get bent out of shape
insultingly
intolerable
fuck off
affront
vex
cut down
get in someone's hair
get up someone's nose
sore
bitch eating crackers
drive to distraction
rub someone the wrong way
twist someone's balls
naggle
temper
cut up rough
give curry
wasp
cut up nasty
frost
incense
furibund
give it large
temperament
burn up
make a nuisance of oneself
nause
upend
agitate
tease
flip out
bug
hulk out
rotted
acerbate
blow a gasket
fret
screw around
butthurt
lapidate
rile
carry
madden
chafe
do one's block
pelt
gadfly
ether