give someone ass cancer
give someone the shits
get someone's goat
comb someone's hair the wrong way
neg
get under someone's skin
mither
tickle the dragon's tail
rub up the wrong way
break someone's balls
boil someone's piss
get someone's back up
raise someone's hackles
bust someone's balls
get under one's goat
get in someone's hair
twist someone's balls
grind one's gears
provoke
get up someone's ass
bug
grig
get someone's Irish up
get someone's dander up
get up someone's nose
spleen
nark
drive someone crazy
do someone's head in
get on someone's tits
test someone's patience
set someone's teeth on edge
rub someone the wrong way
torque off
harass
get on someone's nerves
devil
gripe
screw around
bother
discomfort
offend
get on someone's wick
curl someone's hair
rustle someone's jimmies
gibbet
tease
molest
piss in someone's cornflakes
hock
importune
irk
roil
bite someone's head off
tread on someone's toes
get at
drive someone up the wall
ride
tick off
plague
chap someone's hide
set up someone's birse
vex
make someone's jaw drop
fuck off
make a show of oneself
derange
hulk out
grate
make a spectacle of oneself
give it large
tee off
make someone's flesh creep
ether
dere
smack talk
anger
put out
get a rise out of