do someone's head in
comb someone's hair the wrong way
get under one's goat
grind one's gears
get on someone's nerves
get up someone's ass
enturbulate
break someone's balls
bust someone's balls
neg
rub someone the wrong way
set someone's teeth on edge
get someone's goat
give someone ass cancer
mither
get under someone's skin
grig
get on someone's tits
nark
drive someone crazy
spleen
give someone the shits
inflammatory
irk
annoy
importune
agitate
tickle the dragon's tail
worry
bother
chafe
give it large
boil someone's piss
piss in someone's cornflakes
rustle someone's jimmies
get someone's dander up
get someone's Irish up
tease
raise someone's hackles
harrow
rub up the wrong way
aggravate
get someone's back up
torque off
shit-stir
bait
test someone's patience
drive someone up the wall
foment
get at