turn one's life upside down
blow the roof off
smash
destroy
whemmel
burn one's bridges
mindfuck
train wreck
fuck shit up
discompose
upset
foul one's own nest
self-destruct
fumble the bag
shit in someone's Cheerios
go off the reservation
lay waste
extirpate
devastate
scalp
desecrate
break
muck up
havoc
make mincemeat out of
nuke
disturb the peace
premove
ravage
explode
bereave
go rogue
inorganize
poop on
get in someone's hair
saw off the branch one is sitting on
wreak havoc
subvert
cook someone's goose
holocaust
drive someone crazy
destruct
mindscrew
brainfuck
tickle the dragon's tail
gum
wipe out
mutilate
eviscerate
set the heather on fire
ruin
drive a nail in someone's coffin
crab
neuter
damage
permafuck
botch up
bedash
wreck
sabotage
bitch
hash
metastasize
distract
snatch someone's edges
unsuppress
shit up
come over