discomfort
offend
frustrate
stick in someone's craw
get to
pestilential
importune
irritate
plaguy
upend
provoke
grig
bothersome
nettlesome
trying
get under one's goat
wouldn't you know it
spleen
nark
get on someone's tits
drive someone crazy
hassle
blister
aggravation
shake up
give someone ass cancer
tickle the dragon's tail
torque off
argh
disturbing
consternate
rub someone the wrong way
cock
pain in the butt
mither
annoy
irritating
put the cat among the pigeons
set someone's teeth on edge
irritatingly
ruffle someone's feathers
ruffle some feathers
confronting
comb someone's hair the wrong way
curse it
irritant
thorn
gripe
devil
tease