fettle
have a face on
get up on the wrong side of the bed
suck a lemon
set off
arc up
blow a gasket
flip out
oppress
pack a sad
wind up
shake up
run high
have a cob on
get one's bowels in an uproar
have the blues
go to pieces
sperg
sadden
lose one's temper
pother
cloud
grouch
upset
rustle someone's jimmies
knawvshawl
bum
gloom
acerbate
unsettle
seethe
hurt
exacerbate
pain
anguish
get out of bed on the wrong side
fly off the handle
provoke
depress
forset
lose one's cool
skeeve
fret
qualm
eat away at
soothe
harsh one's mellow
see red
forget to take one's medication this morning
chuck a wobbly
disturb
deject
fall apart
dere
glaum
annoy
orp
grig
peak
embitter
pity
disquiet
mistemper
stress out
drive someone up the wall
irritate
wake up on the wrong side of bed
do one's nut