As you may have noticed, above you will find words for "The observation that, because of the very large number of degrees of freedom in an unfolded polypeptide chain, the molecule has an astronomically large number of possible conformations, and therefore sequentially sampling all the possible conformations is not practical, yet most small proteins fold spontaneously on a millisecond or even microsecond timescale.". Hover the mouse over the word you'd like to know more about to view its definition. Click to find a better fitting word. Finally, thanks to ChatGPT, the overall results have been greatly improved.