the end of one's rope
at the end of one's tether
enough is enough
have had it up to here
that's done it
that does it
exasperated
browned off
cheesed off
last straw
sick and tired
baffled
impatient
noncomposure
intolerance
buay tank
thwarted
restlessness
fuckshit
impatience
du lan
forbearing
try
gimme a break
flustrated
annoyance
cuntshit
vexation
botheration
maddening
yeesh
irritation
frustratingly
fed up
harried
drat
frustrating
harassed
compassion fatigue
can't live with them, can't live without them
patience of Job
annoyed
patience of an angel
curses
disconcerted
pestered
patience of a saint
vexed
overfraught
frustrative
irritate
difficulties
bleargh
mad
wearing
in too deep
infuriation
pissed off
roiled
irritated
enragement
snit
nettled
peeved
impatiently
miffed
riled
pissed
steamed
stung
flounder
frustration
fucksticks
blood and ashes
fuck it
bullocks
nag
fuck this
upsettingness
high blood
problem child
apeshit
peck
d'oh
confuddled
hen-peck
contend
importune
sod this for a game of soldiers
lose one's mind
fussbudgety
smoke
stress puppy
blow this for a game of soldiers
upsettable
kvetchy

English words for 'The limit of one’s patience, when one is so frustrated or annoyed that one can no longer cope.'

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