pain in the ass
discomfort
gadfly
red flag
shock to the system
irritating
nettlesome
doggonit
affliction
botherance
irritant
thorn
sandcorn
pestilential
bitchy-pants
shitkicker
nuisance
bugger
annoyance
infliction
pain in the neck
pain
bother
pain in the arse
botheration
royal pain
agonize
bad news
afflict
screw it
stick in someone's craw
wringer
at
vexation
no picnic
discomforter
overset
bane of someone's life
frustrate
adminicle
the pits
blah
miscreator
evil day
blazes
irritation
bane of someone's existence
growlf
offend
uncanny
pet peeve
hardship
ruffle someone's feathers
torture
pet hate
pestering
undelight
shake up
subject
trying
frustration
enervator
beast
bleargh
Hurtville
curses
ooch
ick
grig
rah
importune
dislike
cunt
wring
squick
annoy
give someone a hard time
tough cookie
bastard
causer
irritate
drag
bugbear
defogger
argh
sodding hell
irritational
poison
bollocks
get to
geebag
lamesauce
rack
blimey O'Riley
fuckness
plaguy