bigtime
outstanding
great
consequential
big
accent
worth talking about
emphasis
import
measurable
monumental
importance
momentous
significatory
of import
important
all important
all-important
essential
crucial
of the essence
instrumental
eminent
especial
historic
hypersignificant
supermajor
momentousness
significative
first-order
capital
paramount
cardinal
preeminent
leading
earthmoving
substantial
material
significant
meaning
granddaddy
pregnant
polar
pivotal
be-all and end-all
father
noticeable
mentionable
top-priority
big deal
to write home about
pitch
heavyweight
top priority
decent
deep
acute
meaningful
adsignification
ponderable
name
red-letter
constitutive
first-line
significance
something to
regardable
significatively
above all
signifying
account
considerable
notandum
pertinent
value
behemothian
importantness
significativeness
centre stage
prima
weight
significantness
high on the totem pole
fundamental
center stage
memorable
imperative
bigtime
outstanding
great
consequential
big
worth talking about
measurable
monumental
momentous
significatory
of import
important
all important
all-important
essential
crucial
of the essence
instrumental
eminent
especial
historic
hypersignificant
supermajor
significative
first-order
capital
paramount
cardinal
preeminent
leading
earthmoving
substantial
material
significant
meaning
pregnant
polar
pivotal
noticeable
mentionable
top-priority
to write home about
heavyweight
decent
deep
acute
meaningful
ponderable
red-letter
constitutive
first-line
regardable
considerable
pertinent
behemothian
prima
high on the totem pole
fundamental
memorable
imperative
significatively
accent
emphasis
import
importance
momentousness
granddaddy
be-all and end-all
father
big deal
pitch
top priority
adsignification
significance
signifying
account
notandum
value
importantness
significativeness
centre stage
weight
significantness
center stage
name
English words for 'Of major significance or importance.'
As you may have noticed, above you will find words for "Of major significance or importance.". Hover the mouse over the word you'd like to know more about to view its definition. Click 
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to pattern after
August
tranquilizing
To set upon
motivate
everything is under control
flows into the North Sea
butting in
to examine and strike the balance of debt and credit
a stroke
medical cannabis
idiomatic phrase
clearly.
old cloth
direct control
truncation
carbon monoxide
divide.
semifinalists
having two rays
to endeavour
to be intimate
magistrate
sperm bank
pay attention!
to affect.
a variety of black bass
ignorance of something.
self-reference.
FTTH
To make different
Excessively
busy period
almanac
abutment
parochial
megalopolis
emergency case
to be superior to
all-you-can-eat
to do thoroughly
coldhearted
ganglion
task force
A town in Texas
scream
mental
treasurer
by some chance
much