quantum
difference
megachange
multichange
affrication
degemination
nasalization
spirantization
radical
inflection
quantum leap
make a difference
transformative
mutandum
transfiguration
nevermind
unsettled
significatory
variation
fluctuation
game-changing
import
uncertain
changing
changemaking
changeable
changefulness
difference-making
motion
zoom
changedness
surgery
commutable
fargoing
consequential
life event
work
act on
raise the stakes
rescope
changingness
watershed
big
move the needle
great
straighten out
on the turn
reform
rejuvenation
see the light
leaven
revolutionize
acceleration
makeover
overturn
revolutionise
moderation
adsignification
play a part
assay
easing
metastasis
relief
movement
significative
new lease of life
drift
tinkering
vicissity
unstable
rechange
weight
mutation
trend
vicissitude
bettering
bigtime
imprint
transitive
adjustmental
on the cusp
turning point
revisional
climate-changing
changefully
fine
relevancy
resignify
tempolabile
heft
make all the difference
of the moment
adjustation
increase
red-letter

English words for 'Of a change, significant.'

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