frontline
dominating
ascendant
ascendent
reign supreme
preeminent
leading
prima
supraessential
particular
special
second-string
head
master
chief
main
primary
principal
high-end
substantial
cutting edge
extremity
supreme
instrumental
high order bit
after
high
meat
essence
pith
marrow
sum
core
heart and soul
centre
predominant
heart
primal
firstborn
base
basis
gist
center
nitty-gritty
constitutive
substance
worth talking about
kernel
nub
inwardness
top-priority
first and foremost
foremost
heavyweight
sovereign
a potiori
order of the day
exploited
first
best-known
inner
right
one and only
lead
intimate
high-profile
internal
bigtime
quasiessential
ripe
good
all-important
paramount
great
kingpin
top priority
granddaddiest
uttermost
uppermost
everything
momentousness
germane
outstanding
name
fundamental
prime
arterial
extreme
centerpiece
be-all and end-all
bigwig
be all and end all
dominant
centrepiece
right-hand

English words for 'Most advanced or important'

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