frontline
ascendant
dominating
ascendent
reign supreme
preeminent
leading
prima
particular
special
supraessential
second-string
head
principal
main
master
primary
chief
high-end
substantial
cutting edge
supreme
extremity
after
instrumental
high order bit
essence
firstborn
kernel
heart
sum
pith
base
centre
high
nub
marrow
meat
nitty-gritty
core
heart and soul
primal
center
constitutive
predominant
substance
worth talking about
basis
inwardness
gist
top-priority
first and foremost
foremost
a potiori
sovereign
heavyweight
order of the day
exploited
best-known
first
lead
internal
bigtime
one and only
ripe
good
quasiessential
all-important
inner
right
high-profile
intimate
kingpin
granddaddiest
paramount
everything
top priority
uppermost
outstanding
great
momentousness
uttermost
germane
extreme
fundamental
arterial
name
prime
be-all and end-all
centrepiece
bigwig
right-hand
centerpiece
dominant
be all and end all

English words for 'Most advanced or important'

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