taxing
baffling
distressedly
perturbedly
care killed the cat
dejectedly
overtroubled
misstress
intend
hyperstress
do one's nut
in low spirits
cryey
solicitous
saddeningly
frustratedly
anaspeptic
upend
upsetting
upsettingly
lamentingly
bowed-down
cut up
toughly
force someone's back to the wall
get one's bowels in an uproar
fucksticks
miserably
hot seat
feel the pinch
horror
exasperatingly
beast
tense
moodily
fearful
distress
lose one's mind
flappish
dire straits
distressfully
overwhelming
frightful
desperate straits
restressable
tumultuously
upsettingness