lunatic
few cards shy of a full deck
mad as a fish
mad
mad as a March hare
one fry short of a Happy Meal
détraqué
daft
spack attack
mad as a box of frogs
batty
doolally tap
meshugge
verklempt
off one's trolley
mad person
maniacal
nutballs
off-minded
half-cracked
bananas
in low spirits
dejectedly
tired
cross
exasperatedly
bonkers
bazonkers
cracky
up the wall
gobsmacked
nut-bar
dementedly
overtense
distraught
tamping
siao
funny in the head
off one's dot
madness
crack up
horror-struck
crazy as a pet coon
overwound
mad as a mongoose
hair-on-fire
psycho
mad as a hatter
kee siao
fruity
inchoate
wobbly
depressedly
doddery
insaniac
p.o.'ed
nuts
dreich
Ophelian
cheerlessly
crazy
sick-ass
pissy
psychotically
unglued
heated
mad as a cut snake
topsy-turvy
daffy
depressoid
paniculately
tremulatory
crazy as a bedbug
toppy
mad as a meat axe
browned off
in a state
go crazy
hot under the collar
despairingly
lamentingly
panickedly
three stops short of Dagenham
flustered
go ballistic
spare
despairfully
lunatical
tame
fucky
miserable as a wet hen
miserable
miserably
anguishedly
wretched
wretchedness
jeeringly
suffering