miff
dither
pother
flap
get up someone's nose
irk
give someone ass cancer
wake up on the wrong side of bed
importune
piss off
get up someone's ass
get someone's goat
cop the needle
fret
hulk out
get under one's goat
neg
fill up
tick off
pester
chap someone's hide
torque off
harass
raise someone's hackles
rub someone the wrong way
get someone's back up
rub up the wrong way
discomfort
provoke
tickle the dragon's tail
grig
get someone's Irish up
get someone's dander up
get under someone's skin
drive someone crazy
break someone's balls
get on someone's tits
offend
nark
spleen