knee-buckler
nerf
starve
destroy
unblessing
degrading
impair
errability
tempestuousness
snatch someone's edges
fragilize
debilitant
semidestructive
have a fable for
unmanning
downiness
haunting
degradedness
acraze
mark
wind egg
fillip
kiss of death
bonus
imbecilitate
turd in the punchbowl
worm in the apple
sodomise
come out in
scathefulness
take its toll
fly in the ointment
blow off course
compensatory
unbearability
unbearableness
detrimentalness
shatterable
wreck
hit
detrimentality
collapse
draining
not a pretty sight
blood sport
exhausting
fragile
-clast
deobstructive
fail at life
hit one hard
tragedy
impoverish
smashup
ebbing
kick someone when they are down
poison
horrendousness
desensitizer
grind down
fault
vanisher
thumbscrew
shrinker
ruinousness
depletor
brisant
for the worse
imperfection
deplorability
blitheness
blemish
shock to the system
nuke
overproneness
go to someone's head
shatteredness
insalubrity
glistening
spoliatory
decline
harrowingly
degradate
bone-chilling
sap
destructibleness
run
scathingness
appallingness
impairment
devitalize
loss
tearable
insalubriousness
laceratingly
degenerate
abase
countercharm
slashing

English words for 'Anything so stunning as to have a weakening effect on a person.'

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